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Functionality for Skin Radiance and Dullness (2): In Vitro Evaluation…

Glycation stress caused by advanced glycation end-products (AGEs) is known to significantly impact skin tone. In particular, the glycation of dermal proteins, such as collagen and elastin, has been shown to contribute not only to skin stiffening and wrinkles but also to a yellowish, dull complexion.

Recent studies have reported that proteins in the stratum corneum also undergo glycation. This process is thought to delay epidermal turnover, leading to progressive skin dullness and a consequent loss of skin translucency.

The inhibitory effect of pineapple ceramide on AGE formation in stratum corneum proteins has been reported. To evaluate its effect on dermal components, Type I collagen was incubated with ribose, a sugar, to induce glycation in the presence of pineapple ceramide. After a two-week incubation period, the resulting AGEs were detected by ELISA using an anti-AGE antibody.

Source：FOOD STYLE21

Supervisor

President
Born in Gunma Prefecture in 1965, he completed his doctoral studies at the Graduate School of Agricultural Science at Tokyo University of Agriculture (PhD), and served as a special research fellow at the Japan Society for the Promotion of Science, a part-time lecturer at Tokyo University of Agriculture, and an associate professor and professor at Takasaki University of Health and Welfare before becoming a professor at Tokyo University of Agriculture in April 2012. He is a professor at the same graduate school, and will be the president of Tokyo University of Agriculture in April 2021. He will be the chairman of Tokyo University of Agriculture in July 2023.

School he attended
April 1984 - March 1988 Graduated from the Department of Forestry (Forestry Science Course), Faculty of Agriculture, Tokyo University of Agriculture

Degrees he received
Tokyo University of Agriculture - Doctor of Forestry

Career history within the university
April 2012 - Ongoing Professor, Department of Forest Science, Faculty of Regional Environmental Science, Tokyo University of Agriculture
April 2016 - Ongoing Director, Food and Agriculture Museum, Tokyo University of Agriculture (Other organizations)
April 2021 - Ongoing President, Tokyo University of Agriculture

Academic societies and committees he has been affiliated with
April 1985 - Ongoing Japan Wood Research Society
June 1988 - Ongoing Japanese Mushroom Society
April 1995 - Ongoing Japanese Society of Inflammatory and Regenerative Medicine
April 1995 - Ongoing Japanese Society of Bioscience, Biotechnology, and Agricultural Chemistry
May 1995 - Ongoing Applied Pharmacology Research Society